Effect Of Thyroid Hormone Derangements On Sexual Function In Men Attending The Primary Health Clinic In Makah City In Saudi Arabia 2022

Abstract

Background:

Sexual dysfunction affects many people, with 33–60% of women reporting sexual dysfunction and 8–52% of men with erectile dysfunction (ED) or premature ejaculation (PE). In an effort to determine the constellation of factors responsible for sexual dysfunction, the effect of thyroid hormone derangements has been of recent interest. Thyroid hormones for its relevance to male reproduction in the last few decades . Hyperthyroidism and hypothyroidism both affect testicular functions and influence neuroendocrine regulations over reproductive functions via the crosstalk between the hypothalamic-pituitary-thyroid axis and the hypothalamic-pituitary-gonadal axis. The alterations in the male reproductive hormonal milieu by thyroid hormones may lead to reduced testosterone levels and deterioration of semen quality. However, there are very few reports on the direct effects of thyroid disorders upon testicular functions and semen quality. Aim of this study: To investigate the associations between thyroid hormones and sexual dysfunction in men in Makah city in Saudi Arabia 2022. Methods: This is a cross-sectional study among the male patients underwent thyroid hormonal test. Study participants have been recruited from united cl[1]inics and King Fahd hospital in Makah city in Saudi Arabia; data were collected via an online validated questionnaire. Our total participants were (40). Results: Among forty participants we found  patients with thyroid abnormality  in IIEFS, the Thyroid dysfunction the majority of participants answer no suffering from thyroid dysfunction were (70.0%), while Yes suffering from thyroid dysfunction were(30.0%), according  the If the answer to the previous question is (yes),  the type of disorder  majority of participants thyroid laziness were (58.3%) followed by thyroid gland activity were(41.7%), regarding the was there a difference in sexual activity the majority of participants were (58.3%), while not suffering from difference in sexual activity were(41.7%).Conclusion: Thyroid dysfunction is an important factor in the pathogenesis of sexual dysfunction in men and possibly women. Evidence suggests a reversibility of sexual dysfunction with correction of thyroid dysfunction, though the exact pathophysiology of thyroid-mediated sexual dysfunction remains unknown. However, current evidence supports thyroid derangements rather than autoantibodies as the causative factor in men, while autoantibodies appear to play a more prominent role in women