Assessment of the Level of Interleukin-17 in Patients with Axial Spondyloarthritis

Abstract

The article presents data from our own studies on the study of the level of pro-inflammatory cytokine - interleukin-17 in patients with axial spondylitis. The level of interleukin-17 was studied in two groups: in patients with spinal ankylosis and in patients without spinal ankylosing, as well as in healthy individuals. The level of interleukin-17 was also compared with the clinical and functional signs of the disease. According to the results of the studies, an increase in the level of interleukin-17 was revealed by 10.5 times compared with healthy individuals and by 1.8 times in patients with no signs of ankylosis. An increase in the level of interleukin-17 shows a high correlation with spinal lesions and clinical and functional signs of the disease, which once again proves its pathogenetic significance in the development of ankylosis.