The Effect of Estrogen on Vaginal Infection with Candidiasis

Abstract

This study was conducted at the University of Kirkuk - College of Education for Pure Sciences - Department of Life Sciences  to determine the effect of estrogen hormone on vaginal infection with candidiasis for women in the city of Kirkuk / Iraq for the period  from August 2022 to October 2022, where 200 vaginal swabs were collected from women who declined Consultant of the Maternity, Gynecology and Children's Hospital and some private clinics. Women are aged 17-0 5 years for investigate Candida SPP types and prepare a  questionnaire list to record patient information.  Laboratory tests, culture and biochemical tests were performed to diagnose Candida. The results of culture on the medium of Sabouraud Dextrose Ager with Chloramphenicol showed the presence of 94 positive cultured samples with  a percentage of 50% of the total and 610 negative  samples for culture and a percentage of 50%. Four types of Candida albicans, Candida tropicalis and Candida glabrata were isolate Candida Lusitaniae by 69%, 22%, 5% and 3% respectively and the diagnosis of fungi was confirmed using polymerase chain reaction technique.

 Theresults showed a significant difference between the category of infected women and non-infected women compared to the control group, where the significance value was equal to (0.046),  which is less than (0.05), while the highest incidence of diabeteswas within the age group 17-28 years.  As for academic achievement, it was among non-educated women, where it reached .6% 26 with a significant difference at the level of probability (0.05 ) and the rate of  infection outside the city was higher, reaching 37%, with a significant difference at the level of probability (0.05 ).